A Quantitative and Qualitative Study of Rat Testis Following Administration of Methadone and Buprenorphine
نویسندگان
چکیده
Article history: Received: 09 Jul 2011 Revised: 11 Sept 2011 Accepted: 25 Nov 2011
منابع مشابه
The Effects of Methadone and Buprenorphine on Testis of Rats
I am writing in response to the article, “A quantitative and qualitative study of rat testis following administration of methadone and buprenorphine” by Zahra Heidari, Hamidreza Mahmoudzadeh-Sagheb & Farhad Kohan in Volume 1(1): 14-17, 2012 (1). This article is addresses an important subject, that of hypogonadism and other changes in seminiferous tubules and testis after administration of metha...
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Opiate addiction is a chronic mental illness with severe repercussion in personal and public health. Various medicaments have been subjected to research in order to find a proper treatment, methadone is the most and wide used drug, buprenorphine/naloxone is the most recent ones, but other choices have been proposed such as prescribing heroin (1). The mentioned treatments, are considered as main...
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Background and Aim: Methadone and buprenorphine are agonist and partial agonist of opioid receptors respectively. Opiates have side effects on various organs specially kidneys. In this study, effects of buprenorphine and methadone on volumetric changes of male rat kidney were investigated. Materials and Methods: In this experimental study, 15 male Wistar rats each weighing 250±15 gr were select...
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Background: The rate of drug dependence and abuse is a growing problem in the Iran, number of opioid – dependent people is estimated at a total of 2000.000-4000.000 individuals. The aim of this study was a Comparison of Methadone and Buprenorphine in the Treatment of Opiate Addiction referring to a treatment clinic of Baharan psychiatric hospital in Zahedan city. Methods: In a cross sect...
متن کاملHypogonadism and Low Testosterone Levels as a Side Effect of Methadone and Buprenorphine
The article is an animal study which addresses an important clinical issue i.e. hypogonadism and low testos-terone levels as a side effect of methadone and buprenor-phine (1). This is not an uncommon side effect which we see in patients receiving long term opioid maintenance treatment. Since methadone has been in use since the 1960s, clinicians became aware of this problem and it is usually add...
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تاریخ انتشار 2012